H. TEELING, B. M. FUCHS, D. BECHER, C. KLOCKOW, A. GARDEBRECHT, C. M. BENNKE, M. KASSABGY, S. HUANG, A. J. MANN, J. WALDMANN, M. WEBER, A. KLINDWORTH, A. OTTO, J. LANGE, J. BERNHARDT, C. REINSCH, M. HECKER, J. PEPLIES, F. D. BOCKELMANN, U. CALLIES, G. GERDTS, A. WICHELS, K. H. WILTSHIRE, F. O. GLÖCKNER, T. SCHWEDER, AND R. AMANN. 2012. Substrate-controlled succession of marine bacterioplankton populations induced by a phytoplankton blom, Science, advanced online publication

KLEINER M, WENTRUP C, LOTT C, TEELING H, WETZEL S, YOUNG J, CHANG JY, SHAH M, VERBERKMOES NC, ZARZYCKI J, FUCHS G, MARKERT S, HEMPEL K, VOIGT B, BECHER D, LIEBEKE M, LALK M, ALBRECHT D, HECKER M, SCHWEDER T, DUBILIER N. 2012. Metaproteomics of a gutless marine worm and its symbiotic microbial community reveal novel pathways for carbon and energy use. PNAS. in press

QUIEL A, JÜRGEN B, GREINACHER A, LASSEN S, WÖRL R, WITT S, SCHWEDER T. 2012. Sensitive detection of idiotypic platelet-reactive alloantibodies by an electrical protein chip. Biosensors & Bioelectronics. in press

VOIGT B, HIEU XC, HEMPEL K, BECHER D, SCHLÜTER R, TEELING H, GLÖCKNER FO, AMANN R, HECKER M, SCHWEDER T. 2012 Cell surface proteome of the marine planctomycete Rhodopirellula baltica. Proteomics. in press

GARDEBRECHT A, MARKERT S, SIEVERT SM, FELBECK H, THÜRMER A, ALBRECHT D, WOLLHERR A, KABISCH J, LE BRIS N, LEHMANN R, DANIEL R, LIESEGANG H, HECKER M, SCHWEDER T. 2012. Physiological homogeneity among the endosymbionts of Riftia pachyptila and Tevnia jerichonana revealed by proteogenomics. ISME J 6(4):766-76

WELSCH N, HOMUTH G, SCHWEDER T. 2012. Suitability of different β-galactosidases as reporter enzymes in Bacillus subtilis. Appl Microbiol Biotechnol. 93(1):381-92

WILMES, B.; KOCK, H.; GLAGLA, S.; ALBRECHT, D.; BODE, R.; DANCHIN, A.; FELLER, G.; HECKER, M. AND SCHWEDER, T. 2011. The cytoplasmic and periplasmic proteome of the psychrophilic bacterium Pseudoalteromonas haloplanktis TAC125 during exponential growth. Appl. Environm. Microbiol. 77, 1276-1283

MARKERT, S.; GARDEBRECHT, A.; FELBECK, H.; SIEVERT, S.M.; KLOSE, J.; BECHER, D.; ALBRECHT, D.; THÜRMER, A.; DANIEL, R.; KLEINER, M.; HECKER, M.; SCHWEDER, T. 2011. Status quo in physiological proteomics of the uncultured Riftia pachyptila endosymbiont. Proteomics, 11(15): 3106-3117

SCHROETER, R.; VOIGT, B.; JÜRGEN, B.; METHLING, K.; PÖTHER, D.C.; SCHÄFER, H.; ALBRECHT, D.; MOSTERTZ, J.; MÄDER, U.; EVERS, S.; MAURER, K.H.; LALK, M.; MASCHER, T.; HECKER, M.; SCHWEDER, T. 2011. The peroxide stress response of Bacillus licheniformis. Proteomics, 11(14): 2851-66

SCHWEDER T. 2011. Bioprocess monitoring by marker gene analysis. Biotechnol J. 6(8):926-33

JUNNE S, KLINGNER A, KABISCH J, SCHWEDER T, NEUBAUER P. 2011. A two-compartment bioreactor system made of commercial parts for bioprocess scale-down studies: Impact of oscillations on Bacillus subtilis fed-batch cultivations. Biotechnol J. 6(8): 1009-17

UHLIG C, KABISCH J, PALM GJ, VALENTIN K, SCHWEDER T, KRELL A. 2011. Heterologous expression, refolding and functional characterization of two antifreeze proteins from Fragilariopsis cylindrus (Bacillariophyceae). Cryobiology. 63(3): 220-8

LOHSSE A, ULLRICH S, KATZMANN E, BORG S, WANNER G, RICHTER M, VOIGT B, SCHWEDER T, SCHÜLER D. 2011. Functional analysis of the magnetosome island in Magnetospirillum gryphiswaldense: the mamAB operon is sufficient for magnetite biomineralization. PLoS One, 6(10):e25561.

VOIGT B, ANTELMANN H, ALBRECHT D, EHRENREICH A, MAURER KH, EVERS S, GOTTSCHALK G, VAN DIJL JM, SCHWEDER T, HECKER M. 2009. Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis. J Mol Microbiol Biotechnol. 16(1-2):53-68

QUIEL A, JÜRGEN B, PIECHOTTA G, LE FOLL AP, ZIEBANDT AK, KOHLER C, KÖSTER D, ENGELMANN S, ERCK C, HINTSCHE R, WEHLAND J, HECKER M, SCHWEDER T. 2010. Electrical protein array chips for the detection of staphylococcal virulence factors. Appl Microbiol Biotechnol. 85(5):1619-1627

JÜRGEN B, BREITENSTEIN A, URLACHER V, BÜTTNER K, LIN H, HECKER M, SCHWEDER T, NEUBAUER P. 2010. Quality control of inclusion bodies in Escherichia coli. Microb Cell Fact. 28;9:41

THANH TN, JÜRGEN B, BAUCH M, LIEBEKE M, LALK M, EHRENREICH A, EVERS S, MAURER KH, ANTELMANN H, ERNST F, HOMUTH G, HECKER M, SCHWEDER T. 2010. Regulation of acetoin and 2,3-butanediol utilization in Bacillus licheniformis. Appl Microbiol Biotechnol. 87(6):2227-35

UEBE R, VOIGT B, SCHWEDER T, ALBRECHT D, KATZMANN E, LANG C, BÖTTGER L, MATZANKE B, SCHÜLER D. 2010. Deletion of a fur-like gene affects iron homeostasis and magnetosome formation in Magnetospirillum gryphiswaldense. J Bacteriol. 192(16):4192-204

WILMES B, HARTUNG A, LALK M, LIEBEKE M, SCHWEDER T, NEUBAUER P. 2010. Fed-batch process for the psychrotolerant marine bacterium Pseudoalteromonas haloplanktis. Microb Cell Fact. accepted

J. MOSTERTZ, F.HOCHGRÄFE, B. JÜRGEN, T. SCHWEDER and M. HECKER. 2008. The role of thioredoxin TrxA in Bacillus subtilis: a proteomics and transcriptomics approach. Proteomics. 8(13):2676-2690

C.X. HIEU, B. VOIGT, D. ALBRECHT, D. BECHER, T. LOMBARDOT, F.O. GLÖCKNER, R. AMANN, M. HECKER and T. SCHWEDER. 2008. Detailed proteome analysis of growing cells of the planctomycete Rhodopirellula baltica. Proteomics. 8(8):1608-23

D. PIOCH, B. JÜRGEN, S. EVERS, K.H. MAURER, M. HECKER AND T. SCHWEDER. 2008. Improved sandwich-hybridization assay for an electrical DNA-chip-based monitoring of bioprocess-relevant marker genes. Appl Microbiol Biotechnol. 78(4):719-728

S. MARKERT, C. ARNDT, H. FELBECK, D. BECHER, S. M. SIEVERT, M. HÜGLER, D. ALBRECHT, J. ROBIDART, S. BENCH, R. A. FELDMAN, M. HECKER, and T. SCHWEDER. 2007. Physiological proteomics of the uncultured endosymbiont of Riftia pachyptila. Science 315(5809):247-250

B. VOIGT, L. T. HOI, B. JÜRGEN, D. ALBRECHT, A. EHRENREICH, B. VEITH, S. EVERS, K.-H. MAURER, M. HECKER. and T. SCHWEDER. 2007. The glucose and nitrogen starvation response of Bacillus licheniformis. Proteomics. 7(3):413-423

M. BORRISS, T. LOMBARDOT, F. O. GLÖCKNER, D. BECHER, D. ALBRECHT and T. SCHWEDER. 2007. Genome and proteome characterization of the psychrophilic Flavobacterium bacteriophage 11b. Extremophiles. 11(1):95-104

M.A. DURBAN, J. SILBERSACK, T. SCHWEDER, F. SCHAUER and U.T. BORNSCHEUER. 2007 High level expression of a recombinant phospholipase C from Bacillus cereus in Bacillus subtilis. Appl Microbiol Biotechnol. 74(3):634-639

D. PIOCH, B. JÜRGEN, S. EVERS, K.-H. MAURER, M. HECKER and T. SCHWEDER. 2007. At-line monitoring of bioprocess-relevant marker genes. Engineering in Life Sciences. 7(4): 373-379

B. VOIGT, T. SCHWEDER, M.J. SIBBALD, D. ALBRECHT, A. EHRENREICH, J. BERNHARDT J, FEESCHE, K.-H. MAURER, G. GOTTSCHALK, J.M. VAN DIJL and M. HECKER. 2006. The extracellular proteome of Bacillus licheniformis grown in different media and under different nutrient starvation conditions. Proteomics. 6(1):268-281

L. T. HOI, B. VOIGT, A. EHRENREICH, D. ALBRECHT, J. FEESCHE, K.-H. MAURER, G. GOTTSCHALK, M. HECKER and T. SCHWEDER. 2006. The phosphate starvation response of Bacillus licheniformis. Proteomics. 6(12):3582-3601

R. PAPA, S. GLAGLA, A. DANCHIN, T. SCHWEDER, G. MARINO and A. DUILIO. 2006. Proteomic identification of a two-component regulatory system in Pseudoalteromonas haloplanktis TAC125. Extremophiles. 10(6):483-491

J. SILBERSACK, B. JÜRGEN, M. HECKER, B. SCHNEIDINGER, R. SCHMUCK and T. SCHWEDER. 2006. An acetoin-regulated expression system of Bacillus subtilis. Appl. Microbiol. Biotechnol. 73(4):895-903

B. ELSHOLZ, R. WÖRL, L. BLOHM, J. ALBERS, H. FEUCHT, T. GRUNWALD, B. JÜRGEN, T. SCHWEDER and R. HINTSCHE 2006. Automated detection and quantitation of bacterial RNA by using electrical microarrays. Analytical Chemistry. 78(14):4794-802

B. JÜRGEN, S. TOBISCH, M. WÜMPELMANN, D. GÖRDES, A. KOCH, K. THUROW, D. ALBRECHT, M. HECKER and T. SCHWEDER 2005. Global Expression Profiling of Bacillus subtilis Cells during Fed-Batch Fermentations with different Nitrogen Sources. Biotechnology & Bioengineering. 92(3):277-298

B. JÜRGEN, K. BUNDVIG BARKEN, S. TOBISCH, D. PIOCH, M. WÜMPELMANN, D. PIOCH, M. HECKER and T. SCHWEDER 2005. Application of an Electrical DNA-Chip for the Expression Analysis of Bioprocess-Relevant Genes of Bacillus subtilis. Biotechnology & Bioengineering. 92(3):299-307

B. VOIGT, T. SCHWEDER, A. EHRENREICH, D. ALBRECHT, J. FEESCHE, K.-H. MAURER, G. GOTTSCHALK and M. HECKER. 2006. The extracellular proteome of Bacillus licheniformis grown in different media and under different nutrient starvation conditions. Proteomics. in press

M. NICKEL, G. HOMUTH, C. BÖHNISCH, U. MÄDER and T. SCHWEDER. 2004. Cold-induction of the Bacillus subtilis bkd operon is mediated by increased mRNA stability. Mol. Gen. Genomics. 272:98-107

M. GABIG-CIMINSKA, A. HOLMGREN, H. ANDRESEN, K. BUNDVIG BARKEN, M. WÜMPELMANN, J. ALBERS, R. HINTSCHE, A. BREITENSTEIN, P. NEUBAUER, M. LOS, A. CZYZ, G. WEGRZYN, G. SILFVERSPARRE, B. JÜRGEN, T. SCHWEDER, S.-O. ENFORS 2004. Electric chips for rapid detection and quantification of nucleic acids. Biosensors and Bioelectronics. 19(6):537-546

B. VOIGT, T. SCHWEDER, D. BECHER, A. EHRENREICH, G. GOTTSCHALK, J. FEESCHE, K.-H. MAURER and M. HECKER. 2004. A proteomic view of cell physiology of Bacillus licheniformis. Proteomics 5:1465-1490

M. BORRISS, E. HELMKE, R. HANSCHKE and T. SCHWEDER. 2003. Isolation and characterization of marine psychrophilic phage-host-systems. Extremophiles. 7(5):377-384

T. SCHWEDER, H. Y. LIN, B. JÜRGEN, A. BREITENSTEIN, S. RIEMSCHNEIDER, V. KHALAMEYZER, A. GUPTA, K. BÜTTNER and P. NEUBAUER. 2002. Role of the general stress response during strong overexpression of a heterologous gene in Escherichia coli. Appl. Microbiol. Biotechnol. 58: 330-337

T. KAAN, G. HOMUTH, J. BANDOW and T. SCHWEDER. 2002. Genome-wide transcriptional profiling of the Bacillus subtilis cold shock response. Microbiol. 148: 3441-3455

S.-O. ENFORS, M. JAHIC, A. ROZKOV, B. XU, M. HECKER, B. JÜRGEN, E. KRÜGER, T. SCHWEDER, G. HAMER , D. O'BEIRNE, N. NOISOMMIT-RIZZI, M. REUSS, L. BOONE, C. HEWITT, C. MCFARLANE, A. NIENOW, T. KOVACS, C. TRÄGÅRDH, L. FUCHS, J. REVSTEDT, P.C. FRIBERG, B. HJERTAGER, G. BLOMSTEN, H. SKOGMAN, S. HJORT, F. HOEKS, H.-Y. LIN, P. NEUBAUER, R. VAN DER LANS, K. LUYBEN, P. VRABEL, AND Å. MANELIUS. 2001. Physiological responses to mixing in large scale bioreactors J. Biotechnol. 85:175-185

B. JÜRGEN, R. HANSCHKE, M. SARVAS, M. HECKER and T. SCHWEDER. 2001. Proteome and Transcriptome based analysis of Bacillus subtilis cells overproducing an insoluble heterologous protein. Appl. Microbiol. Biotech. 55:326-332

L. V. TRUONG, H. TUYEN, E. HELMKE, L. T. BINH and T. SCHWEDER. 2001. Cloning and characterization of two cold-adapted pectate lyases from the marine Antarctic bacterium Pseudoalteromonas haloplanktis strain ANT/505. Extremophiles. 5(1): 35-44

A. BENDT, H. HÜLLER, U. KAMMEL, E. HELMKE and T. SCHWEDER. 2001. Cloning, expression and characterization of a chitinase gene from the Antarctic psychrotolerant bacterium Vibrio sp. Strain Fi:7. Extremophiles. 5(2): 119-126

B. JÜRGEN, H. Y. LIN, S. RIEMSCHNEIDER, C. SCHARF, P. NEUBAUER, R. SCHMID, M. HECKER and T. SCHWEDER. 2000. Monitoring of Genes that Respond to Overproduction of an Insoluble Recombinant Protein in Escherichia coli glucose-limited fed-batch fermentations. Biotech. & Bioeng. 70:217-224

A. ROZKOV, T. SCHWEDER, A. VEIDE and S.O. ENFORS. 2000. Dynamics of proteolysis and its influence on the accumulation of intracellular recombinant proteins. Enzyme Microb. Technol. 27(10):743-748
T. SCHWEDER, A. KOLYSCHKOW, U. VÖLKER and M. HECKER. 1999. Analysis of the expression and function of the _B-dependent general stress regulon of Bacillus subtilis during slow growth. Arch. Microbiol. 171: 439-443

T. SCHWEDER, E. KRÜGER, X. BO, B. JÜRGEN, G. BLOMSTEN, S.O. ENFORS and M. HECKER. 1999. Monitoring of Genes that Respond to Process Related Stress in Large Scale Bioprocesses. Biotech. & Bioeng. 65: 151-159

T. KAAN, B. JÜRGEN and T. SCHWEDER. 1999. The regulation of the expression of the cold shock proteins CspB and CspC in Bacillus subtilis. Mol. Gen. Genet. 262: 351-354

Übersichtsartikel

T. SCHWEDER, S. MARKERT and M. HECKER. 2008. Proteomics of marine bacteria. Electrophoresis. 29(12):2603-2616.

D. PIOCH, T. SCHWEDER and B. JÜRGEN. 2008. Novel developments for improved detection of specific mRNAs by DNA chips. Appl. Microbiol. Biotechnol. In press

T. SCHWEDER, U. LINDEQUIST and M. LALK. 2005. Screening for New Metabolites from Marine Microorganisms. In: Advances in Biochemical Engineering/Biotechnology, Y. Le Gal and R. Ulber eds., Springer. 96:1-23

T. SCHWEDER and M. HECKER. 2004. Monitoring of Stress Responses. In: Advances in Biochemical Engineering/Biotechnology, S.O. Enfors and T. Scheper eds., Springer. 89:47-71

T. SCHWEDER and P. NEUBAUER. 2004. Bioprocess analysis In: Encyclopedia of Analytical Science, P.J. Worsfold, A. Townshend and C.F. Poole eds., Elsevier, pp. 337-344

Buchkapitel

T. SCHWEDER and B. JÜRGEN. 2001. Monitoring of genes that respond to overproduction of insoluble recombinant proteins in Escherichia coli and Bacillus subtilis. In: Recombinant protein production with prokaryotic and eukaryotic cells. A comparative view on host cell physiology, Merten, O.W. et al. eds. Kluwer academic publishers pp. 357-368

U. LINDEQUIST and T. SCHWEDER. 2001. Marine Biotechnology. In: Biotechnology, H.J. Rehm and G. Reed eds., VCH. Vol. 11.

T. SCHWEDER. 1996. The two strategies of biological containment of gentically engineered bacteria. In: Transgenic Organisms. Risk Assessment of Deliberate Release. Birkhäuser Verlag. Zürich. p.113-12

Patente

S. EVERS, K.H. MAURER, L.T. HOI, T. SCHWEDER, M. HECKER B. JÜRGEN, B. VOIGT 2005. Nukleinsäure-bindende Chips zur Detektion von Stickstoffmangelzuständen im Rahmen der Bioprozesskontrolle. DE 022005 070 856.4

S. EVERS, K.H. MAURER, L.T. HOI, T. SCHWEDER, M. HECKER B. JÜRGEN, B. VOIGT 2004. Nukleinsäure-bindende Chips zur Detektion von Phosphatmangelzuständen im Rahmen der Bioprozesskontrolle. DE 102004 061 664.7

T. SCHWEDER, M. HECKER B. JÜRGEN, B. VOIGT, J. FEESCHE, R. BREWES, and K.H. MAURER. 2003. DNA chips used for bioprocess control. PCT/EP2003/009979

T. SCHWEDER and G. HOMUTH. 2003. Kälte-induzierbares Expressionssystem. DE10334811.5
T. SCHWEDER. 2001. Überproduktion kälteangepaßter, thermolabiler Proteine in transgenen Pflanzen. DE101 01 266.7

T. SCHWEDER, H. ANTELMANN and M. HECKER. 2000. Wirts-Vektor-Systeme zur phosphatregulierten Überproduktion von Polypeptiden in Bacillus. PCT EP 01/02877